The grim wreckage of flight BEA 609.
United went on to reach the FA Cup final, but lost at Wembley to Bolton Wanderers, they were also defeated in semi-final of the European Cup by AC Milan. As a mark of respect UEFA invited United to compete in the competition the following season, but the invitation was declined.
While tragedy and football are no strangers, from the relatively recent disasters at Heysel and Hillsbrough to the 66-fans who died at Ibrox in 1971 and 1949's Superga air disaster, which claimed the lives of 18 Torino players, the events and aftermath of Munich still resonate.
Perhaps the sense of loss was so acute and is still remembered today because it stemmed from the loss of young, talented people not yet close to fulfilling their potential.
The Babes may not be young by today's standards when 21-year-old footballs are far from a rarity. The same was not true in 1958. The youngest to perish was Eddie Colman just 21 years and 3 months old; the eldest, the captain of the side, Roger Byrne, who died aged 28.
While the city of Manchester and United as a club felt the loss most acutely, Munich was also a tragedy for English football, European football and the game as a whole and perhaps this is why their memories remain so cherished.
Of those that died Tommy Taylor was already an established part of the England national team with 16 goals in 19 appearances, as was Byrne with 33 caps to his name, while David Pegg had just broken into the national side and Duncan Edwards had broken the post-war record as the youngest player to represent England aged just 18, he went on to win 18 caps.
Charlton still says Edwards is the best player he ever saw play the game. That Charlton played with and against players of the calibre of di Stefano, Beckenbauer, Pele and Best makes such a statement all the more remarkable and further echoes the tragedy of talent lost.
Another reason the Babes are still important today is that their legacy has always been at the forefront of everything Manchester United stands for and strives to attain, and it is as important today as it was 50 years ago.
From the 'Flowers of Manchester' banner inside Old Trafford to the ethos of fast flowing football, complete with an emphasis on youth, employed by Alex Ferguson today, the memory and achievements of Busby and his Babes informs and moulds the club.